Multicenter study of viral etiology and relapse in hospitalized children with bronchiolitis.

ABSTRACT:

Background

It is unclear whether the infectious etiology of severe bronchiolitis affects short-term outcomes, such as posthospitalization relapse. We tested the hypothesis that children hospitalized with rhinovirus (RV) bronchiolitis, either as a sole pathogen or in combination with respiratory syncytial virus (RSV), are at increased risk of relapse.

Methods

We performed a 16-center, prospective cohort study of hospitalized children age <2 years with bronchiolitis. During the winters of 2007-2010, researchers collected clinical data and nasopharyngeal aspirates from study participants; the aspirates were tested using real-time polymerase chain reaction. The primary outcome was bronchiolitis relapse (urgent bronchiolitis visit or scheduled visit at which additions to the bron

SUBMITTER: Hasegawa K 

PROVIDER: S-EPMC4145057 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature