Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns.

ABSTRACT: Based on quantitative cluster analyses of 52 constitutively expressed or behaviorally regulated genes in 23 brain regions, we present a global view of telencephalic organization of birds. The patterns of constitutively expressed genes revealed a partial mirror image organization of three major cell populations that wrap above, around, and below the ventricle and adjacent lamina through the mesopallium. The patterns of behaviorally regulated genes revealed functional columns of activation across boundaries of these cell populations, reminiscent of columns through layers of the mammalian cortex. The avian functionally regulated columns were of two types: those above the ventricle and associated mesopallial lamina, formed by our revised dorsal mesopallium, hyperpallium, and intercalated hyper

SUBMITTER: Jarvis ED 

PROVIDER: S-EPMC4145244 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature