Left ventricular shape variation in asymptomatic populations: the Multi-Ethnic Study of Atherosclerosis.

ABSTRACT:

Background

Although left ventricular cardiac geometric indices such as size and sphericity characterize adverse remodeling and have prognostic value in symptomatic patients, little is known of shape distributions in subclinical populations. We sought to quantify shape variation across a large number of asymptomatic volunteers, and examine differences among sub-cohorts.

Methods

An atlas was constructed comprising 1,991 cardiovascular magnetic resonance (CMR) cases contributed from the Multi-Ethnic Study of Atherosclerosis baseline examination. A mathematical model describing regional wall motion and shape was used to establish a coordinate map registered to the cardiac anatomy. The model was automatically customized to left ventricular contours and anatomical landmarks, corre

SUBMITTER: Medrano-Gracia P 

PROVIDER: S-EPMC4145340 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature