Lymph node dissection during cytoreductive nephrectomy: a retrospective analysis.

ABSTRACT:

Objective

To assess whether regional lymph node dissection could improve the prognosis of patients with metastatic renal cell carcinoma.

Methods

We reviewed data on 258 patients who underwent cytoreductive nephrectomy at Memorial Sloan Kettering Cancer Center, New York, USA, some of whom received a concurrent lymph node dissection. The primary outcome measure was overall survival. A Cox proportional hazards regression model included, age, pathological stage, lymphadenopathy, tumor size, modified Memorial Sloan Kettering Cancer Center criteria, site of metastatic disease and lymph node dissection. We created a logistic regression model to evaluate risk factors for node-positive disease. Survival analyses were carried out for lymph node template (hilar vs other) and number of

SUBMITTER: Feuerstein MA 

PROVIDER: S-EPMC4146659 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature