Meta-analysis of methicillin-resistant Staphylococcus aureus colonization and risk of infection in dialysis patients.

ABSTRACT: Patients undergoing dialysis are particularly vulnerable to methicillin-resistant Staphylococcus aureus (MRSA) infections. We performed a meta-analysis of published studies to estimate the prevalence of MRSA colonization in dialysis patients, time trends, and long-term risk of subsequent MRSA infections. Our search of the PubMed and Embase databases returned 5743 nonduplicate citations, from which we identified 38 relevant studies that included data on 5596 dialysis patients. The estimated prevalence of MRSA colonization was 6.2% (95% confidence interval [95% CI], 4.2% to 8.5%). The prevalence increased over time but remained stable after 2000. Stratification of patients according to dialysis modality and setting revealed that 7.2% (95% CI, 4.9% to 9.9%) of patients on hemodialysis were co

SUBMITTER: Zacharioudakis IM 

PROVIDER: S-EPMC4147983 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature