Epidemiology of disappearing Plasmodium vivax malaria: a case study in rural Amazonia.

ABSTRACT:

Background

New frontier settlements across the Amazon Basin pose a major challenge for malaria elimination in Brazil. Here we describe the epidemiology of malaria during the early phases of occupation of farming settlements in Remansinho area, Brazilian Amazonia. We examine the relative contribution of low-density and asymptomatic parasitemias to the overall Plasmodium vivax burden over a period of declining transmission and discuss potential hurdles for malaria elimination in Remansinho and similar settings.

Methods

Eight community-wide cross-sectional surveys, involving 584 subjects, were carried out in Remansinho over 3 years and complemented by active and passive surveillance of febrile illnesses between the surveys. We used quantitative PCR to detect low-density asexual

SUBMITTER: Barbosa S 

PROVIDER: S-EPMC4148206 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature