Dissociable contributions of ventromedial prefrontal and posterior parietal cortex to value-guided choice.

ABSTRACT: Two long-standing traditions have highlighted cortical decision mechanisms in the parietal and prefrontal cortices of primates, but it has not been clear how these processes differ, or when each cortical region may influence behaviour. Recent data from ventromedial prefrontal cortex (vmPFC) and posterior parietal cortex (PPC) have suggested one possible axis on which the two decision processes might be delineated. Fast decisions may be resolved primarily by parietal mechanisms, whereas decisions made without time pressure may rely on prefrontal mechanisms. Here, we report direct evidence for such dissociation. During decisions under time pressure, a value comparison process was evident in PPC, but not in vmPFC. Value-related activity was still found in vmPFC under time pressure. However, v

SUBMITTER: Jocham G 

PROVIDER: S-EPMC4148525 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature