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Novel replication-competent circular DNA molecules from healthy cattle serum and milk and multiple sclerosis-affected human brain tissue.

ABSTRACT: Epidemiological data point to the involvement of a cow milk factor in the etiology of multiple sclerosis (MS). Eleven circular DNA molecules closely related to transmissible spongiform encephalopathy (TSE)-associated isolate Sphinx 1.76 were isolated from healthy cattle serum, cow milk, and serum and brain tissue from MS patients.

SUBMITTER: Whitley C 

PROVIDER: S-EPMC4148727 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature

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Novel replication-competent circular DNA molecules from healthy cattle serum and milk and multiple sclerosis-affected human brain tissue.

Whitley Corinna C   Gunst Karin K   Müller Hermann H   Funk Mathis M   Zur Hausen Harald H   de Villiers Ethel-Michele EM  

Genome announcements 20140828 4

Epidemiological data point to the involvement of a cow milk factor in the etiology of multiple sclerosis (MS). Eleven circular DNA molecules closely related to transmissible spongiform encephalopathy (TSE)-associated isolate Sphinx 1.76 were isolated from healthy cattle serum, cow milk, and serum and brain tissue from MS patients. ...[more]

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