Species and gene divergence in Littorina snails detected by array comparative genomic hybridization.

ABSTRACT:

Background

Array comparative genomic hybridization (aCGH) is commonly used to screen different types of genetic variation in humans and model species. Here, we performed aCGH using an oligonucleotide gene-expression array for a non-model species, the intertidal snail Littorina saxatilis. First, we tested what types of genetic variation can be detected by this method using direct re-sequencing and comparison to the Littorina genome draft. Secondly, we performed a genome-wide comparison of four closely related Littorina species: L. fabalis, L. compressa, L. arcana and L. saxatilis and of populations of L. saxatilis found in Spain, Britain and Sweden. Finally, we tested whether we could identify genetic variation underlying "Crab" and "Wave" ecotypes of L. saxatilis.

Results

We

SUBMITTER: Panova M 

PROVIDER: S-EPMC4148934 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature