First-trimester placental ultrasound and maternal serum markers as predictors of small-for-gestational-age infants.

ABSTRACT:

Objective

The objective of the study was to combine early, direct assessment of the placenta with indirect markers of placental development to identify pregnancies at greatest risk of delivering small-for-gestational age infants (SGA10).

Study design

We prospectively collected 3-dimensional ultrasound volume sets, uterine artery pulsatility index, and maternal serum of singleton pregnancies at 11-14 weeks. Placental volume (PV), quotient (placental quotient [PQ] = PV/gestational age), mean placental diameter (MPD) and chorionic diameters, and the placental morphology index (PMI = MPD/PQ and adjusts the lateral placental dimensions for quotient) were measured offline. Maternal serum was assayed for placental growth factor and placental protein-13. These variables were evaluat

SUBMITTER: Schwartz N 

PROVIDER: S-EPMC4149853 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature