Extensive homologous recombination in classical swine fever virus: A re-evaluation of homologous recombination events in the strain AF407339.

ABSTRACT: In this short report, the genome-wide homologous recombination events were re-evaluated for classical swine fever virus (CSFV) strain AF407339. We challenged a previous study which suggested only one recombination event in AF407339 based on 25 CSFV genomes. Through our re-analysis on the 25 genomes in the previous study and the 41 genomes used in the present study, we argued that there should be possibly at least two clear recombination events happening in AF407339 through genome-wide scanning. The reasons for identifying only one recombination event in the previous study might be due to the limited number of available CSFV genome sequences at that time and the limited usage of detection methods. In contrast, as identified by most detection methods using all available CSFV genome sequences

SUBMITTER: Chen Y 

PROVIDER: S-EPMC4150228 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature