From Caenorhabditis elegans to the human connectome: a specific modular organization increases metabolic, functional and developmental efficiency.

ABSTRACT: The connectome, or the entire connectivity of a neural system represented by a network, ranges across various scales from synaptic connections between individual neurons to fibre tract connections between brain regions. Although the modularity they commonly show has been extensively studied, it is unclear whether the connection specificity of such networks can already be fully explained by the modularity alone. To answer this question, we study two networks, the neuronal network of Caenorhabditis elegans and the fibre tract network of human brains obtained through diffusion spectrum imaging. We compare them to their respective benchmark networks with varying modularities, which are generated by link swapping to have desired modularity values. We find several network properties that are spe

SUBMITTER: Kim JS 

PROVIDER: S-EPMC4150304 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature