Three-way interactions between mosquito population, viral strain and temperature underlying chikungunya virus transmission potential.

ABSTRACT: Interactions between pathogens and their insect vectors in nature are under the control of both genetic and non-genetic factors, yet most studies on mosquito vector competence for human pathogens are conducted in laboratory systems that do not consider genetic and/or environmental variability. Evaluating the risk of emergence of arthropod-borne viruses (arboviruses) of public health importance such as chikungunya virus (CHIKV) requires a more realistic appraisal of genetic and environmental contributions to vector competence. In particular, sources of variation do not necessarily act independently and may combine in the form of interactions. Here, we measured CHIKV transmission potential by the mosquito Aedes albopictus in all combinations of six worldwide vector populations, two virus str

SUBMITTER: Zouache K 

PROVIDER: S-EPMC4150320 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature