Long-term ultraviolet flux, other potential risk factors, and skin cancer risk: a cohort study.

ABSTRACT:

Background

Few prospective studies have examined the relationship between sun exposure, other potential risk factors, and risk of different skin cancers [including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma] simultaneously.

Methods

We evaluated the association between a number of potential risk factors and skin cancer risk in a cohort of 108,916 US women, the Nurses' Health Study II (1989-2009).

Results

During 2.05 million years of follow-up, we identified 6,955, 880, and 779 diagnoses of BCC, SCC, and melanoma, respectively. Compared with participants in the lowest quintile of cumulative ultraviolet flux in adulthood, participants in the highest quintile had multivariable-adjusted relative risks (RR) of 2.35 (Ptrend < 0.0001) for BCC, 2.5

SUBMITTER: Wu S 

PROVIDER: S-EPMC4151553 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature