Balancing cardiovascular (CV) and cancer death among patients with small renal masses: modification by CV risk.

ABSTRACT:

Objective

To assess modification of comparative cancer survival by cardiovascular (CV) risk and treatment strategy among older patients with small renal masses (SRMs).

Patients and methods

Patients with localised T1a renal cell carcinoma were identified in the Surveillance, Epidemiology and End Results-Medicare database (1995-2007). Patients were stratified by CV risk, using major atherosclerotic CV comorbidities identified by the Framingham Heart Study, to compare overall (OS), cancer-specific (CSS), and CV-specific survival (CVSS) for those who deferred therapy (DT) to those undergoing either partial (PN) or radical nephrectomy (RN). Cox proportional hazards and Fine and Gray competing risks regression adjusted for demographics, comorbidities, and tumour size were performe

SUBMITTER: Patel HD 

PROVIDER: S-EPMC4153794 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature