Ontology highlight
ABSTRACT:
SUBMITTER: Takagi J
PROVIDER: S-EPMC4155493 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Cell reports 20131010 1
The polymerization/depolymerization dynamics of microtubules (MTs) have been reported to contribute to control of the size and shape of spindles, but quantitative analysis of how the size and shape correlate with the amount and density of MTs in the spindle remains incomplete. Here, we measured these parameters using 3D microscopy of meiotic spindles that self-organized in Xenopus egg extracts and presented a simple equation describing the relationship among these parameters. To examine the vali ...[more]