Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study.

ABSTRACT:

Background

The ideal blood pressure (BP) to decrease mortality rates in patients with non-dialysis-dependent chronic kidney disease (CKD) is unclear.

Objective

To assess the association of BP (defined as the combination of systolic BP [SBP] and diastolic BP [DBP] at the individual level) with death in patients with CKD.

Design

Historical cohort between 2005 and 2012.

Setting

All U.S. Department of Veterans Affairs health care facilities.

Patients

651 749 U.S. veterans with CKD.

Measurements

All possible combinations of SBP and DBP were examined in 96 categories from lowest (<80/<40 mm Hg) to highest (>210/>120 mm Hg), in 10-mm Hg increments. Associations with all-cause mortality were examined in time-dependent Cox models with adjustment for releva

SUBMITTER: Kovesdy CP 

PROVIDER: S-EPMC4155539 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature