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Thiol-activated gem-dithiols: a new class of controllable hydrogen sulfide donors.

ABSTRACT: A class of novel thiol-activated H2S donors has been developed on the basis of the gem-dithiol template. These donors release H2S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments.

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC4156246 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature

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Thiol-activated gem-dithiols: a new class of controllable hydrogen sulfide donors.

Zhao Yu Y   Kang Jianming J   Park Chung-Min CM   Bagdon Powell E PE   Peng Bo B   Xian Ming M  

Organic letters 20140820 17

A class of novel thiol-activated H2S donors has been developed on the basis of the gem-dithiol template. These donors release H2S in the presence of cysteine or GSH in aqueous solutions as well as in cellular environments. ...[more]

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