Development and immunity-related microRNAs of the lepidopteran model host Galleria mellonella.

ABSTRACT:

Background

MicroRNAs (miRNAs) are small non-coding RNAs that act as key players in the post-transcriptional regulation of protein synthesis. Although little is known about their role in complex physiological processes such as development and immunity, our knowledge is expanding rapidly, thanks to the use of model systems. The larvae of the greater wax moth Galleria mellonella are now established as model hosts for pathogens that infect insects or humans. To build on our previously-reported comprehensive G. mellonella transcriptome, here we describe the identification and analysis of development and immunity-related miRNAs, thus providing valuable additional data to promote the use of this model host for the analysis of complex processes.

Results

To screen for miRNAs that are

SUBMITTER: Mukherjee K 

PROVIDER: S-EPMC4156658 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature