A trial of in-hospital, electronic alerts for acute kidney injury: design and rationale.

ABSTRACT:

Background

Acute kidney injury is common in hospitalized patients, increases morbidity and mortality, and is under-recognized. To improve provider recognition, we previously developed an electronic alert system for acute kidney injury. To test the hypothesis that this electronic acute kidney injury alert could improve patient outcome, we designed a randomized controlled trial to test the effectiveness of this alert in hospitalized patients. The study design presented several methodologic, ethical, and statistical challenges.

Purpose

To highlight the challenges faced and the solutions employed in the design and implementation of a clinical trial to determine whether the provision of an early electronic alert for acute kidney injury would improve outcomes in hospitalized patie

SUBMITTER: Wilson FP 

PROVIDER: S-EPMC4156885 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature