GABenchToB: a genome assembly benchmark tuned on bacteria and benchtop sequencers.

ABSTRACT: De novo genome assembly is the process of reconstructing a complete genomic sequence from countless small sequencing reads. Due to the complexity of this task, numerous genome assemblers have been developed to cope with different requirements and the different kinds of data provided by sequencers within the fast evolving field of next-generation sequencing technologies. In particular, the recently introduced generation of benchtop sequencers, like Illumina's MiSeq and Ion Torrent's Personal Genome Machine (PGM), popularized the easy, fast, and cheap sequencing of bacterial organisms to a broad range of academic and clinical institutions. With a strong pragmatic focus, here, we give a novel insight into the line of assembly evaluation surveys as we benchmark popular de novo genome assembler

SUBMITTER: Junemann S 

PROVIDER: S-EPMC4157817 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature