Preliminary evidence that sub-chronic citalopram triggers the re-evaluation of value in intimate partnerships.

ABSTRACT: Depression frequently involves disrupted inter-personal relationships, while treatment with serotonergic anti-depressants can interfere with libido and sexual function. However, little is known about how serotonin activity influences appraisals of intimate partnerships. Learning more could help to specify how serotonergic mechanisms mediate social isolation in psychiatric illness. Forty-four healthy heterosexual adults, currently in romantic relationships, received 8 days treatment with the selective serotonin re-uptake inhibitor citalopram (N = 21; 10 male) or placebo (N = 23; 12 male). Participants viewed photographs of unknown, heterosexual couples and made a series of judgements about their relationships. Participants also indicated the importance of relationship features in their own

SUBMITTER: Bilderbeck AC 

PROVIDER: S-EPMC4158381 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature