Appraisal of evidence base for introduction of new implants in hip and knee replacement: a systematic review of five widely used device technologies.

ABSTRACT:

Objective

To determine the evidence of effectiveness and safety for introduction of five recent and ostensibly high value implantable devices in major joint replacement to illustrate the need for change and inform guidance on evidence based introduction of new implants into healthcare.

Design

Systematic review of clinical trials, comparative observational studies, and registries for comparative effectiveness and safety of five implantable device innovations.

Data sources

PubMed (Medline), Embase, Web of Science, Cochrane, CINAHL, reference lists of articles, annual reports of major registries, summaries of safety and effectiveness for pre-market application and mandated post-market studies at the US Food and Drug Administration.

Study selection

The five selecte

SUBMITTER: Nieuwenhuijse MJ 

PROVIDER: S-EPMC4159610 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature