In-depth proteomics characterization of embryogenesis of the honey bee worker (Apis mellifera ligustica).

ABSTRACT: Identifying proteome changes of honey bee embryogenesis is of prime importance for unraveling the molecular mechanisms that they underlie. However, many proteomic changes during the embryonic period are not well characterized. We analyzed the proteomic alterations over the complete time course of honey bee worker embryogenesis at 24, 48, and 72 h of age, using mass spectrometry-based proteomics, label-free quantitation, and bioinformatics. Of the 1460 proteins identified the embryo of all three ages, the core proteome (proteins shared by the embryos of all three ages, accounting for 40%) was mainly involved in protein synthesis, metabolic energy, development, and molecular transporter, which indicates their centrality in driving embryogenesis. However, embryos at different developmental st

SUBMITTER: Fang Y 

PROVIDER: S-EPMC4159651 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature