Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles.

ABSTRACT: We report here that the release mechanism of free camptothecin from self-assembling drug amphiphiles can be regulated by use of different linker groups. Our results highlight the significance of the linker group of drug amphiphiles on the drug release efficiency and their consequent in vitro efficacy.

SUBMITTER: Cheetham AG 

PROVIDER: S-EPMC4160079 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature