Automated synthesis of backbone protected peptides.

ABSTRACT: The synthesis of peptides rich in aggregation prone sequences can be improved with backbone protection. We report the automated introduction of backbone protection to a peptide. This new method was applied in a fully-automated synthesis, giving improved handling, quality and yield of several challenging target sequences.

SUBMITTER: Abdel-Aal AB 

PROVIDER: S-EPMC4161149 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature