Universal disease biomarker: can a fixed set of blood microRNAs diagnose multiple diseases?

ABSTRACT:

Background

The selection of disease biomarkers is often difficult because of their unstable identification, i.e., the selection of biomarkers is heavily dependent upon the set of samples analyzed and the use of independent sets of samples often results in a completely different set of biomarkers being identified. However, if a fixed set of disease biomarkers could be identified for the diagnosis of multiple diseases, the difficulties of biomarker selection could be reduced.

Results

In this study, the previously identified universal disease biomarker (UDB) consisting of blood miRNAs that could discriminate between patients with multiple diseases and healthy controls was extended to the recently reported independent measurements of blood microRNAs (miRNAs). The performance ach

SUBMITTER: Taguchi YH 

PROVIDER: S-EPMC4161864 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature