Clinicopathological features and EGFR gene mutation status in elderly patients with resected non-small-cell lung cancer.

ABSTRACT:

Background

The rapid aging of the population in Japan has been accompanied by an increased rate of surgery for lung cancer among elderly patients. It is thus an urgent priority to map out a treatment strategy for elderly patients with primary lung cancer. Although surgical resection remains standard treatment for early stage non-small-cell lung cancer (NSCLC), it is now essential to confirm the status of epidermal growth factor receptor (EGFR) gene mutations when planning treatment strategies. Furthermore, several studies have reported that EGFR mutations are an independent prognostic marker in NSCLC. However, the relations between age group and the molecular and pathological characteristics of NSCLC remain unclear. We studied the status of EGFR mutations in elderly patients with N

SUBMITTER: Nishii T 

PROVIDER: S-EPMC4161910 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature