Fluorescence adaptive optics scanning laser ophthalmoscope for detection of reduced cones and hypoautofluorescent spots in fundus albipunctatus.

ABSTRACT:

Importance

Fundus albipunctatus (FA) is a form of congenital stationary night blindness characterized by yellow-white spots, which were classically described as subretinal. Although night blindness and delayed dark adaptation are hallmarks of this condition, recent studies have described a macular phenotype, particularly among older patients. Using a fluorescence adaptive optics scanning laser ophthalmoscope (FAOSLO), this study provides in vivo morphologic data at the cellular level in FA.

Objective

To study the cone photoreceptors and the albipunctate spots in FA at single-cell resolution.

Design, setting, and participant

A woman in her 30s with FA underwent a complete ophthalmic examination, including conventional imaging tests, at the University of Rochester. A FA

SUBMITTER: Song H 

PROVIDER: S-EPMC4162840 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature