Assignments of RNase A by ADAPT-NMR and enhancer.

ABSTRACT: We report here backbone (1)H and (15)N assignments for ribonuclease A obtained by using ADAPT-NMR, a fully-automated approach for combined data collection, spectral analysis and resonance assignment. ADAPT-NMR was able to assign 98% of the resonances with 93% agreement with traditional data collection and assignment. Further refinement of the automated results with ADAPT-NMR enhancer led to complete (100%) assignments with 96% agreement with assignments by the traditional approach.

SUBMITTER: Tonelli M 

PROVIDER: S-EPMC4162851 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature