Arterial spin labeling with simultaneous multi-slice echo planar imaging.

ABSTRACT:

Purpose

Simultaneous multi-slice (SMS) echo planar imaging (EPI) is incorporated into two-dimensional (2D) arterial spin labeling (ASL) imaging to produce more slices for measuring perfusion in a larger region of the brain than currently possible with multi-slice EPI.

Methods

Pulsed ASL (PASL) preparations using FAIR and QUIPSS II techniques were combined with SMS-EPI. Testing was performed in four subjects at 3 Tesla. Multiband slice acceleration factors (MB) from MB-2 to MB-5 using 40 averages were evaluated. Comparisons were made quantitatively to PASL 2D EPI and qualitatively to PASL 3D GRASE.

Results

In the 12 slice data set, spatial SNR for the perfusion weighted images averaged across subjects was 3.28 and 3.44 for the two sequential MB-1 acquisitions as contro

SUBMITTER: Feinberg DA 

PROVIDER: S-EPMC4162886 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature