Chlorite dismutases - a heme enzyme family for use in bioremediation and generation of molecular oxygen.

ABSTRACT: Chlorite is a serious environmental concern, as rising concentrations of this harmful anthropogenic compound have been detected in groundwater, drinking water, and soil. Chlorite dismutases (Clds) are therefore important molecules in bioremediation as Clds catalyze the degradation of chlorite to chloride and molecular oxygen. Clds are heme b-containing oxidoreductases present in numerous bacterial and archaeal phyla. This review presents the phylogeny of functional Clds and Cld-like proteins, and demonstrates the close relationship of this novel enzyme family to the recently discovered dye-decolorizing peroxidases. The available X-ray structures, biophysical and enzymatic properties, as well as a proposed reaction mechanism, are presented and critically discussed. Open questions about stru

SUBMITTER: Hofbauer S 

PROVIDER: S-EPMC4162996 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature