Development of impulse control circuitry in children of alcoholics.

ABSTRACT:

Background

Difficulty with impulse control is heightened in children with a family history of alcohol use disorders and is a risk factor for later substance problems. Cross-sectional functional magnetic resonance imaging studies have shown altered impulse control processing in adolescents with a positive family history, yet developmental trajectories have yet to be examined.

Methods

Longitudinal functional magnetic resonance imaging was conducted in children of alcoholic families (family history positive [FH+]; n = 43) and children of control families (family history negative [FH-]; n = 30) starting at ages 7-12 years. Participants performed a go/no-go task during functional magnetic resonance imaging at intervals of 1-2 years, with two to four scans performed per subject. W

SUBMITTER: Hardee JE 

PROVIDER: S-EPMC4163541 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature