Autograft versus nonirradiated allograft tissue for anterior cruciate ligament reconstruction: a systematic review.

ABSTRACT:

Background

An autograft has traditionally been the gold standard for anterior cruciate ligament reconstruction (ACLR), but the use of allograft tissue has increased in recent years. While numerous studies have demonstrated that irradiated allografts are associated with increased failure rates, some report excellent results after ACLR with nonirradiated allografts. The purpose of this systematic review was to determine whether the use of nonirradiated allograft tissue is associated with poorer outcomes when compared with autografts.

Hypothesis

Patients undergoing ACLR with autografts versus nonirradiated allografts will demonstrate no significant differences in graft failure risk, laxity on postoperative physical examination, or differences in patient-oriented outcome scores.

SUBMITTER: Mariscalco MW 

PROVIDER: S-EPMC4163684 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature