Genetics of coronary heart disease with reference to ApoAI-CIII-AIV gene region.

ABSTRACT: Cardiovascular diseases are affected by multiple factors like genetic as well as environmental hence they reveal factorial nature. The evidences that genetic factors are susceptible for developing cardiovascular diseases come from twin studies and familial aggregation. Different ethnic populations reveal differences in the prevalence coronary artery disease (CAD) pointing towards the genetic susceptibility. With progression in molecular techniques different developments have been made to comprehend the disease physiology. Molecular markers have also assisted to recognize genes that may provide evidences to evaluate the role of genetic factors in causation of susceptibility towards CAD. Numerous studies suggest the contribution of specific "candidate genes", which correlate with various rol

SUBMITTER: Agrawal S 

PROVIDER: S-EPMC4163704 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature