Longitudinal trajectories and associated baseline predictors in youths with bipolar spectrum disorders.

ABSTRACT:

Objective

The authors sought to identify and evaluate longitudinal mood trajectories and associated baseline predictors in youths with bipolar disorder.

Method

A total of 367 outpatient youths (mean age, 12.6 years) with bipolar disorder with at least 4 years of follow-up were included. After intake, participants were interviewed on average 10 times (SD=3.2) over a mean of 93 months (SD=8.3). Youths and parents were interviewed for psychopathology, functioning, treatment, and familial psychopathology and functioning.

Results

Latent class growth analysis showed four different longitudinal mood trajectories: "predominantly euthymic" (24.0%), "moderately euthymic" (34.6%), "ill with improving course" (19.1%), and "predominantly ill" (22.3%). Within each class, youths wer

SUBMITTER: Birmaher B 

PROVIDER: S-EPMC4164021 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature