Observations from the IMPROVE trial concerning the clinical care of patients with ruptured abdominal aortic aneurysm.

ABSTRACT:

Background

Single-centre series of the management of patients with ruptured abdominal aortic aneurysm (AAA) are usually too small to identify clinical factors that could improve patient outcomes.

Methods

IMPROVE is a pragmatic, multicentre randomized clinical trial in which eligible patients with a clinical diagnosis of ruptured aneurysm were allocated to a strategy of endovascular aneurysm repair (EVAR) or to open repair. The influences of time and manner of hospital presentation, fluid volume status, type of anaesthesia, type of endovascular repair and time to aneurysm repair on 30-day mortality were investigated according to a prespecified plan, for the subgroup of patients with a proven diagnosis of ruptured or symptomatic AAA. Adjustment was made for potential confoundi

SUBMITTER: IMPROVE trial investigators 

PROVIDER: S-EPMC4164272 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature