Milnacipran for neuropathic pain and fibromyalgia in adults.

ABSTRACT:

Background

Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is sometimes used to treat chronic neuropathic pain and fibromyalgia.

Objectives

To evaluate the analgesic efficacy and adverse effects of milnacipran in the management of chronic neuropathic pain or fibromyalgia.

Search methods

We searched CENTRAL, MEDLINE, and EMBASE to 4th of January 2012, together with reference lists of retrieved papers and reviews.

Selection criteria

We included randomised, double-blind studies of eight weeks duration or longer, comparing milnacipran with placebo or another active treatment in chronic neuropathic pain or fibromyalgia.

Data collection and analysis

We extracted efficacy and adverse event data, and two study authors examined issues of

SUBMITTER: Derry S 

PROVIDER: S-EPMC4164830 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature