The impact of comorbid gastroesophageal reflux disease on endoscopic sinus surgery quality-of-life outcomes.

ABSTRACT:

Background

Chronic rhinosinusitis (CRS) and gastroesophageal reflux disease (GERD) are common entities that overlap in patient demographics. The pathophysiologic role of GERD has yet to be elucidated, but it is postulated that extraesophageal reflux may contribute to worsening symptoms of CRS. This study seeks to investigate whether patients with CRS with and without a history of GERD experience comparable quality-of-life (QOL) improvement after endoscopic sinus surgery (ESS).

Methods

An adult cohort (n = 229) with medically refractory CRS was prospectively assessed following ESS using 3 disease-specific QOL constructs. A patient subset with a history of comorbid GERD was retrospectively identified (n = 72) and preoperative and postoperative QOL were compared to patients wit

SUBMITTER: DeConde AS 

PROVIDER: S-EPMC4165340 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature