SimPACE: generating simulated motion corrupted BOLD data with synthetic-navigated acquisition for the development and evaluation of SLOMOCO: a new, highly effective slicewise motion correction.

ABSTRACT: Head motion in functional MRI and resting-state MRI is a major problem. Existing methods do not robustly reflect the true level of motion artifact for in vivo fMRI data. The primary issue is that current methods assume that motion is synchronized to the volume acquisition and thus ignore intra-volume motion. This manuscript covers three sections in the use of gold-standard motion-corrupted data to pursue an intra-volume motion correction. First, we present a way to get motion corrupted data with accurately known motion at the slice acquisition level. This technique simulates important data acquisition-related motion artifacts while acquiring real BOLD MRI data. It is based on a novel motion-injection pulse sequence that introduces known motion independently for every slice: Simulated Prosp

SUBMITTER: Beall EB 

PROVIDER: S-EPMC4165749 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature