Cerebral malaria retinopathy predictors of persisting neurocognitive outcomes in Malawian children.

ABSTRACT:

Background

Neuropsychological sequelae from pediatric cerebral malaria (CM) have been well-documented. Although malaria-specific retinopathy during acute illness has become a defining criterion for CM, its relationship to neurocognitive sequelae has not been documented. This relationship is important if malaria-specific retinopathy reflects the possible brain neuropathogenesis leading to long-term neurocognitive deficits.

Methods

From 2008 to 2012, 49 Malawian children 4.5-12 years of age surviving retinopathy-positive CM (CM-R) were tested 1-6 yrs after illness with the Kaufman Assessment Battery for Children, 2 edition, the tests of variables of attention and the Achenbach Child Behavior Checklist. In an observational study of a cohort of cerebral malaria survivors, these

SUBMITTER: Boivin MJ 

PROVIDER: S-EPMC4165781 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature