NDNA-Prot: identification of DNA-binding proteins based on unbalanced classification.

ABSTRACT:

Background

DNA-binding proteins are vital for the study of cellular processes. In recent genome engineering studies, the identification of proteins with certain functions has become increasingly important and needs to be performed rapidly and efficiently. In previous years, several approaches have been developed to improve the identification of DNA-binding proteins. However, the currently available resources are insufficient to accurately identify these proteins. Because of this, the previous research has been limited by the relatively unbalanced accuracy rate and the low identification success of the current methods.

Results

In this paper, we explored the practicality of modelling DNA binding identification and simultaneously employed an ensemble classifier, and a new predi

SUBMITTER: Song L 

PROVIDER: S-EPMC4165999 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature