Monitoring air pollution effects on children for supporting public health policy: the protocol of the prospective cohort MAPEC study.

ABSTRACT:

Introduction

Genotoxic biomarkers have been studied largely in adult population, but few studies so far have investigated them in children exposed to air pollution. Children are a high-risk group as regards the health effects of air pollution and some studies suggest that early exposure during childhood can play an important role in the development of chronic diseases in adulthood. The objective of the project is to evaluate the associations between the concentration of urban air pollutants and biomarkers of early biological effect in children, and to propose a model for estimating the global risk of early biological effects due to air pollutants and other factors in children.

Methods and analysis

Two biomarkers of early biological effects, DNA damage by the comet assay and

SUBMITTER: Feretti D 

PROVIDER: S-EPMC4166251 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature