Apgar scores at 10 min and outcomes at 6-7 years following hypoxic-ischaemic encephalopathy.

ABSTRACT:

Aim

To determine the association between 10 min Apgar scores and 6-7-year outcomes in children with perinatal hypoxic-ischaemic encephalopathy (HIE) enrolled in the National Institute of Child Health and Human Development Neonatal Research Network (NICHD NRN) whole body cooling randomised controlled trial (RCT).

Methods

Evaluations at 6-7 years included the Wechsler Preschool and Primary Scale of Intelligence III or Wechsler Intelligence Scale for Children IV and Gross Motor Functional Classification Scale. Primary outcome was death/moderate or severe disability. Logistic regression was used to examine the association between 10 min Apgar scores and outcomes after adjusting for birth weight, gestational age, gender, outborn status, hypothermia treatment and centre.

Result

SUBMITTER: Natarajan G 

PROVIDER: S-EPMC4166405 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature