Quantitative assessment of atrial regional function using motion estimation computed tomography.

ABSTRACT:

Objectives

We validated a novel image-based motion estimation computed tomographic (CT) technique (iME) to quantify atrial regional function in swine in vivo.

Materials and methods

Domestic swine (n = 8) underwent CT scan with intravenous contrast before and after median sternotomy where 15 to 30 glass beads were sutured to the atria to calculate the motion estimation error. Four-dimensional motion vector field was estimated using iME. Area change ratio (%AC) was calculated over the atrial endocardium to assess the surface deformation.

Results

The error between the measured and the calculated coordinates based on motion vector field was 0.76 ± 0.43 mm. The %AC was regionally heterogeneous. The %AC time course was significantly different between the right and the left

SUBMITTER: Ashikaga H 

PROVIDER: S-EPMC4167165 | biostudies-literature | 2014 Sep-Oct

REPOSITORIES: biostudies-literature