The functional anatomy of single-digit arithmetic in children with developmental dyslexia.

ABSTRACT: Some arithmetic procedures, such as addition of small numbers, rely on fact retrieval mechanisms supported by left hemisphere perisylvian language areas, while others, such as subtraction, rely on procedural-based mechanisms subserved by bilateral parietal cortices. Previous work suggests that developmental dyslexia, a reading disability, is accompanied by subtle deficits in retrieval-based arithmetic, possibly because of compromised left hemisphere function. To test this prediction, we compared brain activity underlying arithmetic problem solving in children with and without dyslexia during addition and subtraction operations using a factorial design. The main effect of arithmetic operation (addition versus subtraction) for both groups combined revealed activity during addition in the lef

SUBMITTER: Evans TM 

PROVIDER: S-EPMC4167356 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature