Ontology highlight
ABSTRACT:
SUBMITTER: Hidalgo M
PROVIDER: S-EPMC4167608 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Cancer discovery 20140715 9
<h4>Unlabelled</h4>Recently, there has been an increasing interest in the development and characterization of patient-derived tumor xenograft (PDX) models for cancer research. PDX models mostly retain the principal histologic and genetic characteristics of their donor tumor and remain stable across passages. These models have been shown to be predictive of clinical outcomes and are being used for preclinical drug evaluation, biomarker identification, biologic studies, and personalized medicine s ...[more]