The characteristics of ubiquitous and unique Leptospira strains from the collection of Russian centre for leptospirosis.

ABSTRACT:

Background and aim

Leptospira, the causal agent of leptospirosis, has been isolated from the environment, patients, and wide spectrum of animals in Russia. However, the genetic diversity of Leptospira in natural and anthropurgic foci was not clearly defined.

Methods

The recent MLST scheme was used for the analysis of seven pathogenic species. 454 pyrosequencing technology was the base of the whole genome sequencing (WGS).

Results

The most wide spread and prevalent Leptospira species in Russia were L. interrogans, L. kirschneri, and L. borgpetersenii. Five STs, common for Russian strains: 37, 17, 199, 110, and 146, were identified as having a longtime and ubiquitous distribution in various geographic areas. Unexpected properties were revealed for the environmental Lept

SUBMITTER: Voronina OL 

PROVIDER: S-EPMC4167648 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature