Evaluation of differences in automated QT/QTc measurements between Fukuda Denshi and Nihon Koden systems.

ABSTRACT:

Background

Automatic measurement becomes a preference, and indeed a necessity, when analyzing 1000 s of ECGs in the setting of either drug-inducing QT prolongation screening or genome-wide association studies of QT interval. The problem is that individual manufacturers apply different computerized algorithms to measure QT interval. We conducted a comparative study to assess the outcomes with different automated measurements of QT interval between ECG machine manufacturers and validated the related heart rate correction methods.

Methods and results

Herein, we directly compared these different commercial systems using 10,529 Fukuda Denshi ECGs and 72,754 Nihon Kohden ECGs taken in healthy Japanese volunteers. Log-transformed data revealed an equal optimal heart rate correction

SUBMITTER: Sano M 

PROVIDER: S-EPMC4167700 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature