Cryopreservation of Ovarian Tissue: Detailed Description of Methods for Transport, Freezing and Thawing.

ABSTRACT: Purpose: In many cases cancer therapy leads to an irreversible reduction or even loss of ovarian reserve. Cryopreservation of ovarian tissue with subsequent thawing and re-transplantation of tissue after the cancer is in remission constitutes a promising method to preserve fertility in women. To date, more than 25 cases of live births after re-transplantation of cryopreserved ovarian tissue have been published worldwide. In Germany the first live birth after re-transplantation of cryopreserved tissue was in 2011. Material and Methods: After surgical removal of ovarian tissue in the Gynaecological Clinic of Dresden University, the tissue was sent to the Gynaecological Clinic of Bonn University in a special transport container at 5 °C and was frozen the next day using 1.5 M dim

SUBMITTER: Isachenko V 

PROVIDER: S-EPMC4168540 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature